We are based in the Department of Mathematics at Simon Fraser University (SFU) as part of the MAGPIE research group.
We respectfully acknowledge the xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh Úxwumixw (Squamish), səl̓ilw̓ətaʔɬ (Tsleil-Waututh), q̓íc̓əy̓ (Katzie), kʷikʷəƛ̓əm (Kwikwetlem), Qayqayt, Kwantlen, Semiahmoo and Tsawwassen peoples on whose unceded traditional territories we work and reside.
Led by Dr Ben Ashby, the goal of our research is to better understand the ecology and evolution of hosts and their parasites (“parasite” is taken in the broadest sense of the word to include bacteria and viruses as well as helminths and ticks). We’re especially interested in coevolution, which is a process of reciprocal adaptations by hosts to defend themselves against parasites, and counter-adaptations by parasites to overcome or avoid host defences.
We use mathematical models and simulations to understand how parasites and the infectious diseases they cause evolve, for example to infect a broader or narrower range of hosts, or to become more or less virulent, and in turn, how hosts evolve to defend themselves through traits such as resistance, tolerance, and mate choice. We also collaborate with some fantastic experimentalists to combine theoretical and empirical research.
A short primer on coevolution, coevolutionary arms races, and the different types of fluctuating selection.
We're interested in how non-pharmaceutical interventions such as social distancing can affect the transmission and evolution of pathogens during large-scale outbreaks.
Continue reading: How can we manage disease spread and evolution in pandemics?We're studying how the relationships between ageing and immunity evolve to understand why juveniles are sometimes inherently more susceptible to infection than adults, or vice versa, even after accounting for previous exposure.
Continue reading: How does ageing affect immunity, and vice versa?We’re interested in how environmental (e.g. spatial structure, fitness costs) and genetic (e.g. specificity, epistasis) factors affect the coevolution of traits such as resistance and infectivity.
Continue reading: How do hosts and parasites (co)evolve in complex communities?The second key focus of our research seeks to understand the role that parasites play in the evolution of sex and mating strategies, and in turn, the role that host mating strategies play in the epidemiology and evolution of sexually transmitted infections.
Continue reading: How do parasites influence the evolution of host reproductive strategies?We’re interested in how environmental (e.g. spatial structure, fitness costs) and genetic (e.g. specificity, epistasis) factors affect the coevolution of traits such as resistance and infectivity.
Continue reading: How do environmental and genetic factors affect host-parasite coevolution?We explore how competition drives species to evolve into non-overlapping 'niches', and how this can lead to interesting distributions of species across patches.
Continue reading: How do species evolve to occupy distinct niches?
